Detalhe da pesquisa
1.
Efficacy of therapeutically administered gepotidacin in a rabbit model of inhalational anthrax.
Antimicrob Agents Chemother
; 68(3): e0149723, 2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38358266
2.
Efficacy of Intravenously Administered Gepotidacin in Cynomolgus Macaques following a Francisella tularensis Inhalational Challenge.
Antimicrob Agents Chemother
; 67(5): e0138122, 2023 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37097147
3.
Antibacterial Monoclonal Antibodies Do Not Disrupt the Intestinal Microbiome or Its Function.
Antimicrob Agents Chemother
; 64(5)2020 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152087
4.
The Neutrophilic Response to Pseudomonas Damages the Airway Barrier, Promoting Infection by Klebsiella pneumoniae.
Am J Respir Cell Mol Biol
; 59(6): 745-756, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30109945
5.
Targeting Alpha Toxin To Mitigate Its Lethal Toxicity in Ferret and Rabbit Models of Staphylococcus aureus Necrotizing Pneumonia.
Antimicrob Agents Chemother
; 61(4)2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28115346
6.
Critical Role of Alpha-Toxin and Protective Effects of Its Neutralization by a Human Antibody in Acute Bacterial Skin and Skin Structure Infections.
Antimicrob Agents Chemother
; 60(10): 5640-8, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27401576
7.
Anti-alpha-toxin monoclonal antibody and antibiotic combination therapy improves disease outcome and accelerates healing in a Staphylococcus aureus dermonecrosis model.
Antimicrob Agents Chemother
; 59(1): 299-309, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25348518
8.
7-(4-Alkylidenylpiperidinyl)-quinolone bacterial topoisomerase inhibitors.
Bioorg Med Chem Lett
; 24(23): 5502-6, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25455493
9.
Gepotidacin is efficacious in a nonhuman primate model of pneumonic plague.
Sci Transl Med
; 14(647): eabg1787, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35648812
10.
Staphylococcus aureus in Non-Cystic Fibrosis Bronchiectasis: Prevalence and Genomic Basis of High Inoculum ß-Lactam Resistance.
Ann Am Thorac Soc
; 19(8): 1285-1293, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35213810
11.
Efficacy of a new fluoroquinolone, JNJ-Q2, in murine models of Staphylococcus aureus and Streptococcus pneumoniae skin, respiratory, and systemic infections.
Antimicrob Agents Chemother
; 55(12): 5522-8, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21911568
12.
Comparative effects of carbapenems on bacterial load and host immune response in a Klebsiella pneumoniae murine pneumonia model.
Antimicrob Agents Chemother
; 55(2): 836-44, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21135187
13.
In vivo activity of ceftobiprole in murine skin infections due to Staphylococcus aureus and Pseudomonas aeruginosa.
Antimicrob Agents Chemother
; 54(1): 116-25, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19884364
14.
In vivo activity of the pyrrolopyrazolyl-substituted oxazolidinone RWJ-416457.
Antimicrob Agents Chemother
; 53(5): 2028-33, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19273686
15.
Synthesis and antibacterial activity of 7-(1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-7-yl) quinolones.
Bioorg Med Chem Lett
; 19(17): 4933-6, 2009 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19646867
16.
Candida albicans Augments Staphylococcus aureus Virulence by Engaging the Staphylococcal agr Quorum Sensing System.
mBio
; 10(3)2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31164467
17.
Staphylococcus aureus α toxin potentiates opportunistic bacterial lung infections.
Sci Transl Med
; 8(329): 329ra31, 2016 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26962155
18.
Staphylococcus aureus alpha toxin suppresses effective innate and adaptive immune responses in a murine dermonecrosis model.
PLoS One
; 8(10): e75103, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24098366
19.
Synthesis and antibacterial activity of C6-carbazate ketolides.
Bioorg Med Chem Lett
; 16(24): 6231-5, 2006 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16997549
20.
Identification of a dithiazoline inhibitor of Escherichia coli L,D-carboxypeptidase A.
Antimicrob Agents Chemother
; 49(11): 4500-7, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16251288